HES may refer to
- Harvard Extension School
- Hypertext Editing System
- Home Entertainment Suppliers Pty. Ltd.
- Historical European Swordsmanship
- Hudson Entertainment System Sound Format
- Hypereosinophilic syndrome
- Hydroxyethyl starch
- Alternate spelling for Isis, a goddess in Egyptian mythology
- Hessle railway station, England; National Rail station code HES
- HES School of Economics and Business, Amsterdam
- The IATA identifier of Hermiston Municipal Airport in Hermiston, Oregon
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